Indianapolis at Arizona

Bookmaker.com line – Arizona -2 (48)

       Forget the line and concentrate on the over; 48 should be laid waste by early in the 4^th quarter. The Cardinals receivers should find open space against the Colts defense. And Peyton Manning will move the ball, too. This will be a good time for Arizona to finally work on its running game, as Indy’s front 7 often appeared confused on Monday night against the Dolphins. This one doesn’t mean much to Indy, but another loss at home would be a crusher for Arizona, especially if the Niners go 3-0.